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THC & Tropacocaine, by Otto Snow
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THC is a new miracle medication, used to treat sleep disorders allergies, inflammatory diseases, auto immune disorders, migraines, addictions, post traumatic stress disorder, anorexia, etc.
Syntheses of THC and chemical analogs are described. Human testing are also included. The extraction of THC (eg. 40%, 70% and 92% THC Hash Oil) from cannabis is detailed. Isomerisation: a quick route from cannabidiol.
The discovery of its endogenous ligand, anandamide (a fatty acid amide) has revolutionized the investigation of this new neurotransmitter system. Anandamides have been used in the treatment of insomnia, allergies and post traumatic stress disorder yet remain undeveloped. Anandamides will replaced THC and marijuana because of ease of synthesis; preparation from commonly available grocery store oils (eg. olive oil). Multiple reactions are explained.
Tropacocaine was discovered as a trace alkaloid in Coca leaves from Java. It is longer acting and less toxic than cocaine.
Tropacocaine is prepared from atropine obtained from nightshade plants. The synthesis of tropacocaine from Datura (eg. nightshade) is described and referenced. Reactions have been translated into English. Millions of Americans are addicted to cocaine and crack, yet tropacocaine has never been studied to assess its value as a replacement medication. 400+ refs. Color cover. Laminated.
- Sales Rank: #2517840 in Books
- Published on: 2004-08-31
- Original language: English
- Dimensions: 8.75" h x 6.00" w x .50" l, .70 pounds
- Binding: Paperback
- 182 pages
From the Publisher
Book Includes:
Medical Cannabis: CANNABIS. U.S. (Br.) CANNABIS Cannab; THC; Synhexyl Stereochemical Requirements for Cannabimimetic Activity Cannabinoid Receptors CB2 Agonist Treament of Autoimmunine Disorders CB-2 Receptor Agonist Compounds Inhibition of Cell Proliforation; Cannabinoids in the Treatment of Glaucoma Anandamide Amidase Inhibitors as Analgesic Agents CB1 Agonists for Use in Brain Trauma Erratic Gastrointestial Absorbtion of delta-9-Tetrahydrocannabinol Treating Mental Diseases, Inflammation and Pain with Anandamides
Extraction of Delta-9-Tetrahydrocannabinol from Cannabis Extraction of Cannabis Buds (41% THC Oil) Extraction of Cannabis Buds 2 (40% THC Oil) (92% THC Oil) Preparing Delta-9-Tetrahydrocannabinol Reprocessing of the Residue Left After Fractional Distillation of Cannabis Extracts (82% THC Yellow Oil); THC Syntheses Water Soluble Derivatives of Cannabinoids Synthesis of Compound (4) Ketones from Nitriles THC in the Treatment of Glaucoma in Patients who can not take Beta-blockers Compositions useful as a cannabinoid receptor probe Production of 6,12-Dihydro-6-hydroxy-cannabidiol Production of trans-delta-9-Tetrahydrocannabinol Production of 6,12-Dihydro-6-hydroxy-cannabidiol Production of trans-delta-9-Detrahydrocannabinol Preparation of cis-p-Menth-2-ene-1,8,-diol Novel Tetrahydrocannabinol Type Compounds Preparation of (-)-6a,10a-trans-6a,7,8,10a-Tetrahydrodibenzo[b,d]-pyrans Preparation of Optically Active trans-Hexahydrodibenzopyranones 1-Hydroxy-3-(1,1-dimethylheptyl)-6,6-dimethyl-6,6aR,7,8,10,10aR-hexahydro-9-H-dibenzo[b,d]pyran-9-one Producing 6a,10a-trans-6a,7,8,10a-Tetrahydrodibenzo (b,d)-pyrans 3-(1,2-Dimethylheptyl)-6a,7,10,10a-tetra-hydro-1-hydroxy-6,6,9-trimethyl-6H-dibenzo [b,d]pyran
5-Alkylresorcinols: Preparation of l-Hydroxy-2,6-dimethoxy-4-(tertiaryalkyl)benzene 1-Hydroxy-2,6-dimethoxy-4-(1,1-dimethylheptyl)benzene Divarin Dimethyl Ether from 3,4,5-Trimethoxy-propiophenone Reduction of Ketones to Resorcinols Synthesis of 5-Alkylresorcinols; Synthesis of 5-Ethylresorcinol Preparation of Hexylresorcinol by Electrolytic Reduction of Hexanoylresorcinol Synthesis of 5-Methylresorcinol (Orcinol) 5-Alkylresorcinol from Demethylation of 1-(Alkyl)-3,5-Dimethoxybenzene Demethylation Using Pyridine 5-(1,1-dimethylheptyl)resorcinol Demethylation Using 48% Hydrobromic Acid 5-(1,1-Dimethylheptyl)resorcinol ; Preparation of 5-Alkoxyresorcinols Preparation of Phloroglucinol and its Mono-ethers Preparation of Compounds with Marijuana Activity Formation of Tetrahydrocannabinols by Isomerization of Cannabidiol A. By p-toluenesulfonic acid; B. By sulfuric acid; C. By pyridine hydrochloride; D. By phosphoric acid; E. Sulfamic acid; zinc chloride
Converting cis-Hexahydrodibenzo[b,d]pyran-9-ones to trans-Hexahydrodibenzo[b,d]-pyran-9-ones dl-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl) -6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H- dibenzo[b,d]pyran-9-one dl-trans-1-Hydroxy-3-n-pentyl-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one dl-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one Stereoselective Preparation of Hexahydrodibenzopyranones and intermediates (-)-trans-1-Hydroxy-3-(1,1-dimethyl-heptyl)-6,6-dimethyl-6,6a,7,8,10,10a-hexahydro-9H-dibenzo[b,d]pyran-9-one; Acetylation of THC
Delta 1-THC-7-oic acid Analgesic and Anti-inflammatory Agents Platelet Activating Factor Antagonist Non-psychoactive Derivatives of ∆6-THC-7-oic Acid which have Analgesic and Anti-inflammatory Properties Synthesis of (3R,4R)-∆6-THC-DMH-7-oic Acid Acetate
Andanamides: Fatty Acid Amides; Preparation of Arachidonyl Ethanolamide Compounds Isolated from the Brain and Synthesized Synthetic Compounds Prepared and Tested Anandamide Amidase Inhibitors as Analgesic Agents Treating Anxiety and Mood Disorders with Oleamide
Fatty Acid Amides Preparation from Common Household Oils Preparation of Oleamide The Reactions Used N-Substituted Amides of Natural Fatty Acids Preparation of N-Methyl Linseed Oil Fatty Acid Amide Preparation of N-Cyclohexyl Linseed Oil Fatty Acid Amide Preparation of Lauric Diethanolamide from Lauroyl Chloride Preparation of Cocoa Fatty Acid Amide Using the Aminolysis Method
Industrial Manufacture of Fatty Acid Ethanolamides reparation of Oleic Acid Monoethanolamide Purification of Fatty Acid Amides Using Urea Preparation of Olive Oil and Coconut Oil Ethanolamides Preparation of Fatty Acids; Isolation of Linoleic Acid Isolation of Oleic Acid from Olive Oil; Production of Monoalkyolamines
TROPACOCAINE
Coca, The Source of Cocaine; COCAINA. U.S., Br.; COCAINE HYDROCHLORIDUM. U.S., Br. Atropine and the Tropeines Cocaine and the Local Anesthetic; Tropacocaine Benzoyl Ester of Ecgonine Using Benzoic Anhydride Tropacocaine from Pseudo-tropine & Benzoic Anhydride Pseudotropine by Electrolytic Reduction of Tropine Tropineone by Oxidation of Tropine; Extraction of Pseudotropine Pseudotropine by the Electrolytic Reduction of Tropinone Tropinone by the Oxydation of Tropine; Tropinone by the Oxydation of Pseudotropine Tropinone by the Electrolytic Reduction of Tropine or Pseudotropine Benzoic Anhydride
Narcotic Daturas Origin of the Name Jimson, or Jamestown Weed; The Huaca-Cachu of Peru Datura Alkaloids ; Hyoscyamine and Atropine; Atropine Sulphate Hyoscine or Scopolamine ; Extraction of Atropine Growing Datura and Related Species BELLADONNA Atropa belladonna; Atropa belladonna (Belladonna) Cultivation Datura stramonium L. (Jimson Weed) ; Datura stramonium (Jimson weed) Cultivation Hyoscyamus niger (Henbane) Cultivation ; Solanum nigram L. (Black Nightshade)
Anyone interested in the construction and future of CB-1 agonists (eg. THC, Oleamide) or cocaine agonists (eg. tropacocaine) will find this book cutting edge.
Most helpful customer reviews
3 of 3 people found the following review helpful.
Good book
By Walt
This book is very informative on all aspects of cocaine and THC. Gives detailed instructions of synthesis of the two chemicals in a step by step manner. Although I must say the synthesis part is not for everyone, and normal layman, or home chemist, without a solid degree in organic chemistry will be banging their head on the wall trying to figure things out. Other than that the history, medical uses, and origins of cocaine and THC is written in a very easy to understand form. I really like this book and basically ever other book by Otto Snow. This book also isn't to much of clandestine cookbook, but do let me scare you away if your plans were anything like mine :)
0 of 0 people found the following review helpful.
Very bad book just copied some chemical writings from around 1900
By Bernd Stein
Very bad book just copied some chemical writings from around 1900, we know that chemistry was in it's beginning at this time
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